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B12-deficient breeders Edema Hemorrhages Beak shortening Myotrophy of legs and perosis Fattiness of the liver, heart, and kidneys Fewer myelinated fibers in the spinal cord high incidence of embryonic death at 17 days of incubation Although several concerns can be seen in vitamin B12-deficient chickens, the occurrence can still be considered highly unlikely or rare if they are regularly fed a complete diet or grown on litter where animal-based ingredients are used

Most cosmetic sources recommend rotating actives instead of layering them

However some people may have symptoms of vitamin B12 deficiency despite normal vitamin B12 blood test results, or may have low blood levels despite having no symptoms